贾东升,男,博士,副研究员,博士生导师。从事水稻病毒与介体昆虫的互作机理研究。研究成果揭示了在我国新发生的水稻病毒在介体昆虫体内增殖和突破组织屏障、免疫屏障和垂直传播屏障的新机制,以第一或通讯作者在Nature Microbiology、Autophagy、Science China Life Science、PLoS Pathogens、Journal of Virology、Current Opinion in Virology、昆虫学报等病毒学专业杂志发表论文20余篇。主持国家自然科学基金面上项目、青年基金、重点研发子课题、福建省杰出青年基金、福建省自然科学基金面上项目等基金8项,指导国家和省级大员工创新创业项目5项。荣获教育部2022年度高等学校科学研究优秀成果奖(科学技术)自然科学奖二等奖1项,福建省2016年度自然科学奖二等奖1项,授权专利2项,入选糖果派对“金山学者学术新秀”,荣获校“优秀教师”称号。
学习和工作简历:
2001.9-2005.7:西北农林科技大学,农学专业,本科;
2005.9-2008.7:西北农林科技大学,遗传育种专业,硕士;
2009.9-2013.7:糖果派对,植物病理学专业,博士;
2013.8-2017.8:糖果派对,讲师;
2017.9-至今:糖果派对,副研究员。
研究领域:
植物病毒学:水稻病毒与介体昆虫的互作机理。
承担课程:
《农业植物病理学》,本科课程;
《分子生物学实验课》,研究生课程。
主持科研项目:
福建省自然科学基金杰青项目(2020J06015):介体白背飞虱内质网相关降解途径调控南方水稻黑条矮缩病毒适应于高温高效增殖的机制,(2020.11-2023.11),30万;
国家自然科学基金面上项目(31970160):水稻条纹花叶病毒激活介体昆虫多胺合成通路促进病毒侵染的机制,(2020.1-2023.12),59万;
国家重点研发计划项目(2018YFD0201500):柑橘黄龙病病原-媒介-寄主互作及新型防控技术研究,(2018.7-2020.12),36万;
国家自然科学基金面上项目(31770166):卵黄原蛋白介导水稻矮缩病毒利用共生菌突破介体经卵传播屏障的机制,(2018.1-2021.12),64万;
福建省自然科学基金面上项目(2017J01435):叶蝉共生菌Nasuia在水稻矮缩病毒经卵传播过程中的作用机制,(2017.4-2020.4),9万;
糖果派对杰青项目(XJQ201507):共生菌Sulcia介导RDV经卵传播机制的研究,(2015.9-2018.9),30万;
国家自然科学基金青年项目(31400136):昆虫RNAi抗病毒免疫途径调控SRBSDV与不同介体间存在亲和性差异的机制研究,(2015.1-2017.12),25万;
福建省教育厅重点项目(JK2014011):灰飞虱RNAi抗病毒途径对SRBSDV的调控机制,(2014.9-2016.9),5万;
糖果派对校内重点项目(K13XJJ01A):南方水稻黑条矮缩病毒与不同介体飞虱亲和性差异的分子机理(2014.1-2016.12),2万;
指导国家级大员工创新创业项目:SRBSDV编码结构蛋白在Sf9细胞中的定位及致病性,(2016.6-2017.5),2万;
指导国家级大员工创新创业项目:利用灰飞虱培养细胞研究水稻黑条矮缩病毒的增殖机制,(2015.6-2016.5),2万;
指导省级大员工创新创业项目(201410389042):SRBSDV通过“交通工具”在介体昆虫体内扩散的模式,(2014.6-2015.5),1万。
发明专利:
贾东升,魏太云,陈红燕,吴维,陈倩. 一种稻飞虱血淋巴内病毒蛋白的免疫荧光标记检测方法,发明专利,ZL201410319850.8
陈倩, 魏太云, 陈红燕, 贾东升, 毛倩卓, 吴维. 一种亚克力水稻昆虫饲养笼及水稻昆虫饲养方法.发明专利. ZL201410065152.X
获奖和荣誉:
教育部高等学校科学研究优秀成果奖(科学技术)自然科学奖,二等奖,2022
第十四届福建省自然科学优秀学术论文奖,一等奖,2020
2019年糖果派对优秀教师荣誉称号,2019
福建省2016年自然科学奖,二等奖,2017
神农福建农业科技奖,一等奖,2017
第十二届福建省自然科学优秀学术论文奖,三等奖,2016
入选糖果派对“金山学者学术新秀”,2015
第十一届福建省自然科学优秀学术论文奖,三等奖,2014
发表学术论文:
Jia D, Liang Q, Chen H, Liu H, Li G, Zhang X, Chen Q, Wang A, Wei T. Autophagy mediates a direct synergistic interaction during co-transmission of two distinct arboviruses by insect vectors. Science China Life Sciences, 2023. 66, https://doi.org/ 10.1007/s11427-022-2228-y.
Jia D, Liang Q, Liu H, Li G, Zhang X, Chen Q, Wang A, Wei T. A nonstructural protein encoded by a rice reovirus induces an incomplete autophagy to promote viral spread in insect vectors. PLoS Pathog. 2022, 18(5):e1010506.
Jia D, Liu H, Zhang J, Wan W, Wang Z, Zhang X, Chen Q, Wei T. Polyamine-metabolizing enzymes are activated to promote the proper assembly of rice stripe mosaic virus in insect vectors. Stress Biology, 2022, 2:10
Jia D, Luo G, Shi W, Liu Y, Liu H, Zhang X and Wei T. Rice gall dwarf virus promotes the propagation and transmission of Rice stripe mosaic virus by co-infected insect vectors. Front. Microbiol. 2022, 13:834712.
Chen Q, Jia D(共一), Ren J, Cheng Y, Wu H, Guo S, Wei T. VDAC1 balances mitophagy and apoptosis in leafhopper upon arbovirus infection. Autophagy. 2022 Nov 29:1-15.
Yu X, Jia D(共一), Wang Z, Li G, Chen M, Liang Q, Zhou Y, Liu H, Xiao M, Li S, Chen Q, Chen H, Wei T. A plant reovirus hijacks endoplasmic reticulum-associated degradation machinery to promote efficient viral transmission by its planthopper vector under high temperature conditions. PLoS Pathog. 2021, 17(3):e1009347.
Zhao P, Sun X, Li P, Sun J, Yue Y, Wei J, Wei T, Jia D*. Infection characteristics of Rice stripe mosaic virus in the body of the vector leafhoppers. Front. Microbiol. 2019, 9:3258.
Mao Q, Wu W, Liao Z, Li J, Jia D, Wei J, Wei T. Viral pathogens hitchhike with insect sperm for paternal transmission. Nature Communications, 2019, 10: 955.
Jia D, Chen Q, Mao Q, Zhang X, Wu W, Chen H, Yu X, Wang Z, Wei T. Vector mediated transmission of persistently transmitted plant viruses. Current Opinion in Virology. 2018, 28:127-132.
Jia D, Mao Q, Chen Y, Liu Y, Chen Q, Wu W, Zhang X, Chen H,Li Y, Wei T. Insect symbiotic bacteria harbours viral pathogens for transovarial transmission. Nature Microbiology. 2017, 2: 17025.
Jia D, Han Y, Sun X, Wang Z, Du Z, Chen Q, Wei T. The speed of tubule formation of two fijiviruses corresponds with their dissemination efficiency in their insect vectors. Virology Journal. 2016, 13(1):174.
Jia D, Mao Q, Chen H, Wang A, Liu Y, Wang H, Xie L, Wei T. Virus-induced tubule: a vehicle for rapid spread of virions through basal lamina from midgut epithelium in the insect vector. Journal of Virology. 2014, 88(18):10488-10500.
Jia D, Chen H, Zheng A, Chen Q, Liu Q, Xie L, Wu Z, Wei T. Development of an insect vector cell culture and RNA interference system to investigate the functional role of fijivirus replication protein. Journal of Virology. 2012, 86(10): 5800-5807.
Jia D, Guo N, Chen H, Akita F, Xie L, Omura T, Wei T. Assembly of the viroplasm by viral non-structural protein Pns10 is essential for persistent infection of rice ragged stunt virus in its insect vector. Journal of General Virology. 2012, 93(10): 2299-2309.
Jia D, Chen H, Mao Q, Liu Q, Wei T. Restriction of viral dissemination from the midgut determines incompetence of small brown planthopper as a vector of Southern rice black-streaked dwarf virus. Virus Research. 2012, 167(2): 404-408.
Liu Y, Jia D(共同第一), Chen H, Chen Q, Xie L, Wu Z, Wei T. The P7-1 protein of southern rice black-streaked dwarf virus, a fijivirus, induces the formation of tubular structures in insect cells. Archives of Virology. 2011, 156(10): 1729-1736.
Mao X, Jia D(共同第一), Li A,Zhang X, Jing R. Transgenic expression of TaMYB2A confers enhanced tolerance to multiple abiotic stresses in Arabidopsis. Functional Integrative Genomics. 2011, 11:445-465.
李盼,张洁,岳玥,陈红燕,吴维,魏太云,贾东升*. 水稻条纹花叶病毒对介体电光叶蝉生长繁殖及取食行为的影响. 昆虫学报, 2020, 63(2): 174-180.
贾东升,马元元,杜雪,陈红燕,谢联辉,魏太云. 水稻黑条矮缩病毒在灰飞虱消化系统的侵染和扩散过程. 植物病理学报,2014, 44(2): 188-194.
贾东升,任堂雨,陈红燕,魏太云,谢联辉. 白背飞虱体内RNAi技术的建立. 糖果派对学报(自然科学版),2013, 42(6):579-583..
陈红燕,李俊卿,刘宇艳,郭年梅,魏太云,贾东升*. 干扰水稻齿叶矮缩病毒(RRSV)非结构蛋白Pns6的表达阻碍病毒在褐飞虱体内的增殖. 农业生物技术学报, 2015, 23(11): 1488-1493.
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