汤蔚，男，博士，副研究员，硕士生导师。入选福建省级高层次人才、糖果派对金山学者青年学术新秀、校杰青，专注于重要植物病原真菌的致病机制研究，目前已发表SCI论文20余篇，其中第一作者或通讯作者论文12篇，包括Environmental Microbiology、Molecular Plant Pathology、Molecular Plant等一区论文6篇；先后主持国家自然科学基金青年项目、福建省自然科学基金面上项目以及校杰出青年基金等；担任Frontiers in Celluar and Infection Microbiology、Frontiers in Fungal Biology客座编辑，Molecular Microbiology、Environmental Microbiology Report、Applied Microbiology and Biotechnology等国际SCI期刊审稿人。担任福建省级科技特派员及团队发起人。

教育经历

2006年9月-2010年6月，南京农业大学糖果派对，农学学士；

2010年9月-2015年6月，南京农业大学糖果派对植物病理系，农学博士；

2015年8月-2018年12月，糖果派对植物病理系，助理研究员；

2019年1月-2022年5月，糖果派对植物病理系，特任副教授；

2022年6月至今，糖果派对植物病理系，副研究员。

科研项目

1. 国家自然科学基金青年项目：稻瘟病菌内质网相关蛋白质降解途径关键基因MoHrd1的作用机制研究，(2017-2019)，主持；

2. 福建省自然科学基金面上项目：信号肽酶MoSpc2在稻瘟病菌致病过程中的作用机制，(2022-2025)，主持；

3. 福建省自然科学基金青年创新项目：稻瘟病菌转录因子FlbC的致病机理研究，(2016-2019) ，主持；

4. 第五批校杰青项目：泛素E3连接酶MoHrd1及其组分MoDer1在稻瘟病菌的致病机制研究，(2017-2020)，主持；

5. 校科技创新专项基金：分泌蛋白MoCwp1在稻瘟病菌生长发育过程中的功能研究，(2021-2022)，主持；

6. 植保学院青年基金项目：基于泛素化蛋白质组学研究稻瘟病菌泛素连接酶MoHrd1介导的致病机制研究，(2016-2018) ，主持。

发表论文

1. Zhang J, Chen X, Yang Z, Xu H, Weng S, Wang Z*, Tang W*. Endoplasmic reticulum membrane protein MoScs2 is important for asexual development and pathogenesis of Magnaporthe oryzae. Front Microbiol. 2022 Aug 4;13:906784.

2. Aron O, Otieno FJ, Tijjani I, Yang Z, Xu H, Weng S, Guo J, Lu S, Wang Z*, Tang W*. De novo purine nucleotide biosynthesis mediated by MoAde4 is required for conidiation, host colonization and pathogenicity in Magnaporthe oryzae. Appl Microbiol Biotechnol. 2022 Sep;106(17):5587-5602.

3. Aron O, Wang M, Mabeche AW, Wajjiha B, Li M, Yang S, You H, Cai Y, Zhang T, Li Y, Wang B, Zhang D, Wang Z*, Tang W*. MoCpa1-mediated arginine biosynthesis is crucial for fungal growth, conidiation, and plant infection of Magnaporthe oryzae. Appl Microbiol Biotechnol. 2021 Aug;105(14-15):5915-5929.

4. Aron O, Wang M, Lin L, Batool W, Lin B, Shabbir A, Wang Z*, Tang W*. MoGLN2 Is Important for Vegetative Growth, Conidiogenesis, Maintenance of Cell Wall Integrity and Pathogenesis of Magnaporthe oryzae. J Fungi. 2021 Jun 8;7(6):463.

5. Duan G, Bao J, Chen X, Xie J, Liu Y, Chen H, Zheng H, Tang W*, Wang Z*. Large-Scale Genome Scanning within Exonic Regions Revealed the Contributions of Selective Sweep Prone Genes to Host Divergence and Adaptation in Magnaporthe oryzae Species Complex. Microorganisms. 2021 Mar 9;9(3):562

6. Tang W, Jiang H, Aron O, Wang M, Wang X, Chen J, Lin B, Chen X, Zheng Q, Gao X, He D, Wang A, Wang Z. Endoplasmic reticulum-associated degradation mediated by MoHrd1 and MoDer1 is pivotal for appressorium development and pathogenicity of Magnaporthe oryzae. Environ Microbiol. 2020 Dec;22(12):4953-4973

7. Zhong Z, Lin L, Zheng H, Bao J, Chen M, Zhang L, Tang W*, Ebbole DJ*, Wang Z*.Emergence of a hybrid PKS-NRPS secondary metabolite cluster in a clonal population of the rice blast fungus Magnaporthe oryzae. Environ Microbiol. 2020 Jul;22(7):2709-2723.

8. Tang W, Jiang H, Zheng Q, Chen X, Wang R, Yang S, Zhao G, Liu J, Norvienyeku J, Wang Z. Isopropylmalate isomerase MoLeu1 orchestrates leucine biosynthesis, fungal development, and pathogenicity in Magnaporthe oryzae. Appl Microbiol Biotechnol. 2019 Jan;103(1):327-337.

9. Jiang H^#, Lin L^#, Tang W^#(co-first author), Chen X, Zheng Q, Huang J, Yang T, Su L, Dong Y, Wang B, Wang Z. Putative interaction proteins of the ubiquitin ligase Hrd1 in Magnaporthe oryzae. Evol Bioinform Online. 2018 Dec 7;14:1176934318810990.

10. Zhong Z, Chen M, Lin L, Han Y, Bao J, Tang W, Lin L, Lin Y, Somai R, Lu L, Zhang W, Chen J, Hong Y, Chen X, Wang B, Shen WC, Lu G, Norvienyeku J, Ebbole DJ, Wang Z. Population genomic analysis of the rice blast fungus reveals specific events associated with expansion of three main clades. ISME J. 2018 Aug;12(8):1867-1878.

11. Bao J^#, Chen M^#, Zhong Z^#, Tang W^#(co-first author), Lin L, Zhang X, Jiang H, Zhang D, Miao C, Tang H, Zhang J, Lu G, Ming R, Norvienyeku J, Wang B, Wang Z. PacBio Sequencing Reveals Transposable Elements as a Key Contributor to Genomic Plasticity and Virulence Variation in Magnaporthe oryzae. Mol Plant. 2017 Nov 6;10(11):1465-1468.

12. Tang W, Gao C, Wang J, Yin Z, Zhang J, Ji J, Zhang H, Zheng X, Zhang Z, Wang P. Disruption of actin motor function due to MoMyo5 mutation impairs host penetration and pathogenicity in Magnaporthe oryzae. Mol Plant Pathol. 2018 Mar;19(3):689-699.

13. Wang J, Yin Z, Tang W, Cai X, Gao C, Zhang H, Zheng X, Wang P, Zhang Z. The thioredoxin MoTrx2 protein mediates reactive oxygen species (ROS) balance and controls pathogenicity as a target of the transcription factor MoAP1 in Magnaporthe oryzae. Mol Plant Pathol. 2017 Dec;18(9):1199-1209.

14. Yin Z, Tang W, Wang J, Liu X, Yang L, Gao C, Zhang J, Zhang H, Zheng X, Wang P, Zhang Z. Phosphodiesterase MoPdeH targets MoMck1 of the conserved mitogen-activated protein (MAP) kinase signaling pathway to regulate cell wall integrity in rice blast fungus Magnaporthe oryzae. Mol Plant Pathol. 2016 Jun;17(5):654-668.

15. Zhong Z, Norvienyeku J, Chen M, Bao J, Lin L, Chen L, Lin Y, Wu X, Cai Z, Zhang Q, Lin X, Hong Y, Huang J, Xu L, Zhang H, Chen L, Tang W, Zheng H, Chen X, Wang Y, Lian B, Zhang L, Tang H, Lu G, Ebbole DJ, Wang B, Wang Z. Directional Selection from Host Plants Is a Major Force Driving Host Specificity in Magnaporthe Species. Sci Rep. 2016 May 6;6:25591.

16. Tang W, Ru Y, Hong L, Zhu Q, Zuo R, Guo X, Wang J, Zhang H, Zheng X, Wang P, Zhang Z. System-wide characterization of bZIP transcription factor proteins involved in infection-related morphogenesis of Magnaporthe oryzae. Environ Microbiol. 2015 Apr;17(4):1377-96.

17. 王如锋，陈江峰，林定山，云英子，王宗华，汤蔚. 番茄枯萎病菌转录因子FolMsn2的生物学功能[J].植物保护学报,2022,49(02):486-496.

18. 陈浩，王敏，杨子峰，廖煌，吴欢，凌菡，汤蔚. 稻瘟病菌MoSCJ1基因的生物学功能分析[J].糖果派对学报(自然科学版),2021,50(03):309-316.

19. 王如锋，文佳，赵桂媛，王敏，陈雪杭，Osakina Aron，王宗华，汤蔚. MoHRD3基因参与调控稻瘟病菌的生长发育和致病力[J].植物病理学报,2020,50(01):68-79.

E-mail: tangweifafu@126.com    tangw@fafu.edu.cn